HORDB

ID: hor006597
Uniprot ID: Q9IA09
Protein name: GnRH-associated peptide 3
Gene name: gnrh3
Organism: Dicentrarchus labrax (European seabass) (Morone labrax)
Family: GnRH family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Dicentrarchus (genus), Moronidae (family), Eupercaria incertae sedis, Eupercaria, Percomorphaceae, Euacanthomorphacea, Acanthomorphata, Ctenosquamata, Eurypterygia, Neoteleostei, Euteleosteomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Sequence: SVGELEATIRMMGTGEVVSLPEEASAQTQERLRPYNVINDDSSHFD
Length: 46
Propeptide: MEANSRVMVRVLLLALVVQVTLSQHWSYGWLPGGKRSVGELEATIRMMGTGEVVSLPEEASAQTQERLRPYNVINDDSSHFDRKKRSPNK
Signal peptide: MEANSRVMVRVLLLALVVQVTLS
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor006597_AF2.pdb

hor006597_ESM.pdb

Mass:	588337	Formula:	C214H341N61O78S2
Absent amino acids:	CKW	Common amino acids:	E
pI:	3.99	Basic residues:	4
Polar residues:	14	Hydrophobic residues:	13
Hydrophobicity:	-53.91	Boman Index:	-10896
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	74.13
Instability Index:	3511.74	Extinction Coefficient cystines:	1490
Absorbance 280nm:	33.11

PubMed ID: 11086295
Title: Differential expression of three different prepro-GnRH (gonadotrophin-releasing hormone) messengers in the brain of the european sea bass (Dicentrarchus labrax).